Dr. Ramani Rheumatology Clinic
Dr. Ramani
Rheumatology Clinic
Specialist rheumatology care · Kuala Lumpur

EGPA (Churg-Strauss Syndrome)

EGPA is rare and serious, and it often shows itself first as changing asthma or nerve symptoms in someone with a strong allergy history. I try to spot that pattern early because the condition can affect nerves, lungs, skin, kidneys and heart.

Let me explain

What egpa (churg-strauss syndrome) is

Eosinophilic granulomatosis with polyangiitis, previously called Churg-Strauss syndrome, is a rare type of vasculitis. It involves inflammation of small and medium blood vessels and is often associated with asthma, sinus disease and high eosinophil counts.

What patients may notice

Symptoms to look out for

Asthma that changes or becomes difficult to control

Sinus symptoms, nasal polyps or persistent congestion

Numbness, weakness or nerve pain in hands or feet

Rashes, fever, weight loss or night sweats

Breathlessness, chest symptoms or abdominal pain in some patients

Rheumatology perspective

Why this matters to a rheumatologist

Rheumatology is involved because EGPA is an immune-mediated vasculitis that may affect nerves, lungs, skin, kidneys, heart and other organs. Diagnosis relies on pulling the whole picture together rather than any single test.

When to seek help

Signs I would like you to seek care for

For emergency symptoms please seek urgent or emergency care first rather than waiting for a WhatsApp reply.

Asthma with unexplained nerve symptoms or rash

Coughing blood, chest pain or severe breathlessness

Weakness or numbness affecting a limb

Fever, weight loss or systemic illness with high eosinophils

How I can help

What a specialist review looks like

I review asthma and allergy history, examine for vasculitis signs, check blood counts and inflammation markers, and coordinate imaging, urine tests or specialist input depending on organ involvement.

Frequently asked

Questions my patients often ask me

No. Asthma can be part of EGPA, but EGPA is a systemic vasculitis.

Speak with me

If you are worried about EGPA symptoms, or your asthma is changing alongside new nerve, skin or systemic symptoms, WhatsApp my clinic and we can help you decide whether a rheumatology assessment is the right next step.

This page is for general education only and does not replace medical advice. Please consult a qualified healthcare professional for diagnosis and treatment.