Remicade (infliximab)
Also known as: Infliximab · Remicade · Remsima · Inflectra
Infliximab, sold as Remicade and several biosimilars, is a biologic infusion used in inflammatory arthritis when tablets are not enough. It is one of the original biologics and still an important option.
Calm, careful medication review by a consultant rheumatologist.
What this medicine is
Infliximab is a monoclonal antibody that blocks TNF, a key driver of joint and skin inflammation. It is given as a drip into a vein, usually every few weeks, at a day-care unit.
Uses and context
It is used in rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis and other spondyloarthritis, often when injection biologics are not suitable or not enough.
How this relates to rheumatology care
Before starting, I screen carefully for TB, hepatitis and other infections. Infusions are scheduled at the hospital day-care unit and take a few hours, with observation for reactions. I review response and safety at each visit.
What safety checks may matter
TB screening before starting
Hepatitis B and C screening
Vaccination review before starting
Baseline blood counts and liver function
Infusion setting with staff trained to manage reactions
Side effects and red flags
If you have emergency symptoms such as severe allergic reaction, breathing difficulty, chest pain, stroke-like symptoms, severe abdominal pain, vomiting blood, black stools, sudden vision loss, severe infection symptoms, or severe weakness or confusion, please seek urgent medical care first rather than waiting for a WhatsApp reply.
Rash, itching, breathlessness or fever during or after infusion
Persistent fever, chills or cough
New shortness of breath
Signs of severe allergic reaction
A new or changing skin lesion
New neurological symptoms
Things worth knowing day to day
Avoid live vaccines while on infliximab.
Tell surgeons and dentists that you are on a biologic before procedures.
Do not delay treating suspected infections; contact me early.
Long gaps between doses can increase risk of infusion reactions on restart.
Questions patients often ask me about this medicine
Speak with me
If Remicade or an infliximab biosimilar has been suggested, please message my clinic. I would like to explain what to expect and help you plan your infusion schedule.
Other medications used in rheumatology care
This page is for general education only and does not replace medical advice. Please consult a qualified healthcare professional for diagnosis and treatment. Do not start, stop, or change any medicine without advice from your doctor.